Glucose metabolism
Preclinical studies have examined its role in glucose uptake and insulin sensitivity via AMPK.
20 mg lyophilized vial · Mitochondrial peptide (16 amino acids)
Metabolism, straight from the mitochondria. A peptide encoded in mitochondrial DNA, studied in preclinical research for its role in metabolic homeostasis and insulin sensitivity.
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The science behind
MOTS-c is a 16-amino-acid peptide encoded within the mitochondrial genome rather than in the cell nucleus's DNA. It belongs to the family of mitochondrial-derived peptides (MDPs), signaling molecules that cells produce from their energy core.
In the scientific literature, MOTS-c has been studied as a metabolic regulator: preclinical research has explored its relationship with the AMPK pathway, glucose metabolism, and energy homeostasis. Its levels decline with age, which is why it interests research on metabolic aging and longevity.
The TrüPeptides vial contains 20 mg of lyophilized MOTS-c at ≥99% purity, synthesized to pharmaceutical-grade standards and validated by HPLC and mass spectrometry. It is distributed exclusively as a research-grade compound; it is not a medicine and is not intended for human consumption.
Preclinical research
These are the lines of inquiry the scientific community has explored in preclinical models. None constitutes a therapeutic promise or an indication for use.
Preclinical studies have examined its role in glucose uptake and insulin sensitivity via AMPK.
Model research has explored its relationship with physical endurance and the muscular response to exercise.
As a peptide of mitochondrial origin, its role in cellular energy signaling has been investigated.
Because its levels decline with age, it has been studied in models of metabolic homeostasis and longevity.
Compliance note: the information above summarizes findings from preclinical and model research. It should not be interpreted as evidence that MOTS-c diagnoses, treats, cures, or prevents any disease in humans.
Compound data sheet
Verifiable data for the TrüPeptides MOTS-c 20 mg vial.
| Name | MOTS-c (mitochondrial-derived peptide) |
|---|---|
| Sequence | 16 amino acids encoded in the mitochondrial genome (12S rRNA) |
| Presentation | 20 mg vial, lyophilized powder |
| Purity | ≥ 99% |
| Analytical method | High-performance liquid chromatography (HPLC) + mass spectrometry (MS) |
| Solubility | Bacteriostatic water (not included) |
| Storage | Refrigerated at 2–8 °C, protected from light and humidity |
| Shelf life (lyophilized) | 24 months when stored as directed |
| Category | Longevity · Research-grade compound |
| Origin & quality control | Synthesis to GMP standards · batch-level Certificate of Analysis |
Safety first
Research-grade product. TrüPeptides MOTS-c is intended for laboratory research use only. It is not a medicine, has not been evaluated by INVIMA, and is not approved to diagnose, treat, cure, or prevent any disease, nor for human consumption.
Laboratory tool
Work out the concentration and volume per measure when reconstituting your vial. A reference calculation for laboratory handling.
A reference calculation for laboratory handling; it is not a dosing recommendation or advice for human use.
Radical transparency
Truth in every vial. Every batch of MOTS-c we ship arrives with its own Certificate of Analysis, verifiable in seconds by scanning the QR code printed on the packaging.
The COA reports ≥99% purity confirmed by HPLC and validates the peptide identity and molecular weight by mass spectrometry (MS). So you are not buying a label — you are buying evidence.
How to read our COAScan the QR code on your vial to view your batch's real certificate anytime.
Common questions
MOTS-c is a 16-amino-acid peptide encoded within the mitochondrial genome. Preclinical studies have explored its role in metabolic homeostasis, glucose metabolism, and the response to exercise. It is sold exclusively as a research-grade compound and is not a medicine.
No. The MOTS-c 20 mg vial ships lyophilized (as a powder), and bacteriostatic water is not included; it is purchased separately for reconstitution in the laboratory. The product requires refrigeration between 2 and 8 °C and protection from light.
Every batch from TruPeptides arrives with a Certificate of Analysis (COA) that you can verify via a QR code. The COA reports ≥99% purity confirmed by high-performance liquid chromatography (HPLC) and by mass spectrometry (MS), which validates the peptide's identity and molecular weight.
We ship with Coordinadora and Servientrega across Colombia, with estimated delivery of 24 to 48 hours in major cities such as Bogotá, Medellín, and Cali. Every shipment travels with gel packs to maintain the cold chain to your door. Orders over $250.000 COP ship free.
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